A 5-minute self-assessment to understand your personal risk profile before working with psychedelics. Created by a certified psychedelic coach.
Start the Assessment →Educational content only — not medical advice, not therapy, not a clinical diagnosis. For harm reduction purposes only.
Your psychological history is the strongest predictor of how psychedelics will affect you. Answer honestly — this is for your safety only.
1. Have you ever been diagnosed with schizophrenia, schizoaffective disorder, or any psychotic disorder? ⚠ Hard Stop
2. Have you ever experienced a manic or hypomanic episode (diagnosed bipolar I)? ⚠ Hard Stop
3. Does anyone in your immediate family (parent or sibling) have a history of schizophrenia, bipolar I, or psychotic illness?
4. Do you experience dissociation — feeling detached from yourself or reality — outside of substance use?
5. Do you currently have moderate-to-severe depression or anxiety that is unmanaged?
6. Have you had active suicidal thoughts in the past 12 months? ⚠ Hard Stop
7. Do you have a significant history of unprocessed trauma (childhood adversity, complex PTSD)?
8. Have you ever experienced HPPD — persistent visual disturbances after a previous psychedelic experience? ⚠ Hard Stop
Psychedelics — and especially MDMA — raise heart rate and blood pressure. Some physical conditions significantly increase physiological risk.
9. Have you been diagnosed with a heart condition (arrhythmia, coronary disease, congenital defect, or prior heart attack)?
10. Do you have uncontrolled high blood pressure?
11. Do you have epilepsy or a history of seizures? ⚠ Hard Stop
12. Do you have significant liver or kidney disease?
13. Are you currently pregnant or breastfeeding? ⚠ Hard Stop
14. How is your general physical health right now?
Drug combinations are the #1 preventable cause of serious psychedelic adverse events. Some interactions are life-threatening. Answer carefully.
15. Are you currently taking an MAOI? ⚠ Hard Stop
Examples: phenelzine, tranylcypromine, selegiline, or Syrian rue preparations
16. Are you currently taking an SSRI or SNRI antidepressant?
Examples: fluoxetine, sertraline, escitalopram, venlafaxine, duloxetine
17. Are you currently taking lithium? ⚠ Hard Stop
18. Are you taking any antipsychotic medication?
19. Are you taking blood pressure medications, stimulants, or cardiovascular drugs?
20. Have you used alcohol, cannabis, or other substances in the past 24 hours?
21. Do you have a pattern of heavy or problematic substance use?
Timothy Leary's concept of "set and setting" remains the most important determinant of psychedelic experience quality. These aren't soft factors — they're everything.
22. How would you describe your emotional state over the past 2 weeks?
23. Do you have a clear, positive intention for this experience?
24. Do you have a safe, familiar, comfortable environment prepared?
25. Will you have a sober, trusted person present or available (a sitter)?
26. Do you have significant external stressors right now? (crisis, bereavement, legal issues, major conflict)
27. Have you done preparation work? (reading, journaling, meditation, speaking with an experienced guide)
28. Do you have a plan for integration after the experience?
Knowing what to expect dramatically reduces panic responses. Preparation is itself a safety factor.
29. Have you used psychedelics before?
30. Do you understand the effects, duration, and risks of the substance you're considering?
31. Do you know what to do — or who to call — if the experience becomes overwhelming?
Optional but recommended — this adds substance-specific risk flags to your result. Select all that apply. Skip if you'd prefer not to say.
Vladislav's "10 Rules for Avoiding a Bad Trip" — a practical harm-reduction guide for psychonauts. PDF, free, no spam.
Founder of Entheogen Expert and O!Sapiens. Dedicated to destigmatizing psychedelics through science, education, and open access to information. Since 2023, building tools that make harm-reduction knowledge available to everyone.
Going deeper after your journey? O!Sapiens is a 10-pillar science-backed mental resilience framework — built for psychedelic integration, nervous system regulation, and sustainable transformation. Ideal for people navigating altered states, high-performers facing burnout, and anyone seeking embodied change.
Explore O!Sapiens →