🌿 Science-Based · Harm Reduction · Free

Are You Ready for Your
Entheogenic Journey?

A 5-minute self-assessment to understand your personal risk profile before working with psychedelics. Created by a certified psychedelic coach.

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Based on clinical trial screening criteria Evidence-based ~5 minutes Private — nothing sent or stored

Educational content only — not medical advice, not therapy, not a clinical diagnosis. For harm reduction purposes only.

Section 1 of 6 — Psychiatric History

Your Psychological Background

Your psychological history is the strongest predictor of how psychedelics will affect you. Answer honestly — this is for your safety only.

1. Have you ever been diagnosed with schizophrenia, schizoaffective disorder, or any psychotic disorder? ⚠ Hard Stop

⚠ Psychedelics can significantly exacerbate psychotic disorders. This is a strong contraindication — we strongly recommend speaking with a psychiatrist before considering any entheogenic experience.

2. Have you ever experienced a manic or hypomanic episode (diagnosed bipolar I)? ⚠ Hard Stop

⚠ Diagnosed bipolar I is a significant contraindication. Psychedelics can trigger manic episodes. Consult a psychiatrist first.

3. Does anyone in your immediate family (parent or sibling) have a history of schizophrenia, bipolar I, or psychotic illness?


4. Do you experience dissociation — feeling detached from yourself or reality — outside of substance use?


5. Do you currently have moderate-to-severe depression or anxiety that is unmanaged?


6. Have you had active suicidal thoughts in the past 12 months? ⚠ Hard Stop

⚠ If you are experiencing active suicidal ideation, please reach out to a mental health professional or crisis service before anything else. Your wellbeing comes first.

7. Do you have a significant history of unprocessed trauma (childhood adversity, complex PTSD)?


8. Have you ever experienced HPPD — persistent visual disturbances after a previous psychedelic experience? ⚠ Hard Stop

⚠ A history of HPPD means further psychedelic use carries a high risk of worsening these symptoms. Please consult a specialist.
Section 2 of 6 — Physical Health

Your Physical Health

Psychedelics — and especially MDMA — raise heart rate and blood pressure. Some physical conditions significantly increase physiological risk.

9. Have you been diagnosed with a heart condition (arrhythmia, coronary disease, congenital defect, or prior heart attack)?


10. Do you have uncontrolled high blood pressure?


11. Do you have epilepsy or a history of seizures? ⚠ Hard Stop

⚠ Active seizure disorders are a contraindication for psychedelic use. Consult your neurologist first.

12. Do you have significant liver or kidney disease?


13. Are you currently pregnant or breastfeeding? ⚠ Hard Stop

⚠ Psychedelic use during pregnancy or breastfeeding carries unknown but potentially serious risks to the infant. This is a clear contraindication.

14. How is your general physical health right now?

Section 3 of 6 — Medications & Substances

What You're Currently Taking

Drug combinations are the #1 preventable cause of serious psychedelic adverse events. Some interactions are life-threatening. Answer carefully.

15. Are you currently taking an MAOI? ⚠ Hard Stop
Examples: phenelzine, tranylcypromine, selegiline, or Syrian rue preparations

⚠ MAOI + MDMA can be fatal (serotonin syndrome). MAOI + classic psychedelics also carries serious risk. This is a hard contraindication. Do not combine.

16. Are you currently taking an SSRI or SNRI antidepressant?
Examples: fluoxetine, sertraline, escitalopram, venlafaxine, duloxetine


17. Are you currently taking lithium? ⚠ Hard Stop

⚠ Lithium + psychedelics significantly increases seizure risk. This is a hard contraindication. Do not combine.

18. Are you taking any antipsychotic medication?


19. Are you taking blood pressure medications, stimulants, or cardiovascular drugs?


20. Have you used alcohol, cannabis, or other substances in the past 24 hours?


21. Do you have a pattern of heavy or problematic substance use?

Section 4 of 6 — Set & Setting

Your Mindset & Environment

Timothy Leary's concept of "set and setting" remains the most important determinant of psychedelic experience quality. These aren't soft factors — they're everything.

22. How would you describe your emotional state over the past 2 weeks?


23. Do you have a clear, positive intention for this experience?


24. Do you have a safe, familiar, comfortable environment prepared?


25. Will you have a sober, trusted person present or available (a sitter)?


26. Do you have significant external stressors right now? (crisis, bereavement, legal issues, major conflict)


27. Have you done preparation work? (reading, journaling, meditation, speaking with an experienced guide)


28. Do you have a plan for integration after the experience?

Section 5 of 6 — Experience & Knowledge

Your Experience Level

Knowing what to expect dramatically reduces panic responses. Preparation is itself a safety factor.

29. Have you used psychedelics before?


30. Do you understand the effects, duration, and risks of the substance you're considering?


31. Do you know what to do — or who to call — if the experience becomes overwhelming?

Section 6 of 6 — Substance-Specific

Which Substance Are You Considering?

Optional but recommended — this adds substance-specific risk flags to your result. Select all that apply. Skip if you'd prefer not to say.

Skip & get results
🌿
Vladislav
Certified Psychedelic Coach · Harm Reduction Educator · Barcelona

Founder of Entheogen Expert and O!Sapiens. Dedicated to destigmatizing psychedelics through science, education, and open access to information. Since 2023, building tools that make harm-reduction knowledge available to everyone.

Going deeper after your journey? O!Sapiens is a 10-pillar science-backed mental resilience framework — built for psychedelic integration, nervous system regulation, and sustainable transformation. Ideal for people navigating altered states, high-performers facing burnout, and anyone seeking embodied change.

Explore O!Sapiens →